By Malcolm Carruthers
Simply what's the andropause? even supposing reputation of the andropause idea through the scientific neighborhood is starting to be, it truly is nonetheless a hotly debated factor. yet as a hectic clinician you've sufferers to regard and also you desire info. So the place are you able to locate the data you must comprehend, diagnose, and deal with this situation? Androgen Deficiency within the grownup Male: factors, analysis and therapy distills the information obtained by means of writer Dr. Malcolm Carruthers in his 25 years of study and scientific adventure in diagnosing and treating the andropause right into a complete, specific scientific resource.
Dr. Carruthers records the historical past of the quest for testosterone therapy from antiquity to the awarding of the Nobel Prize to Adolf Butenandt and Leopold Ruzicka for synthesizing testosterone and patenting its creation a few 4,000 years later. He discusses the reasons of androgen deficiency, the male menopause or andropause, and up to date advances in its analysis. The textual content comprises reports of the literature in each one part and a fund of bibliographic references gleaned from the author's years of analysis during this box. this mix of gains makes Androgen Deficiency within the grownup Male: reasons, prognosis and remedy a useful and functional medical advisor, a whole and particular reference quantity, and a cohesive and readable textbook.
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Additional info for Androgen deficiency in the adult male : causes, diagnosis, and treatment
5 He then decided that the method of preparation was too much like hard work, and thought up the much more commercial way by which testosterone is made to this day. He methodically worked out its structure and then produced it, as does the body, from cholesterol, its natural precursor. He sent his paper on this process and the structure of testosterone itself to the German Journal of Physiological Chemistry on 24 August 19356. Just 1 week later a Swiss chemical journal received a paper from Leopold Ruzicka7, a Yugoslavian chemist working for the Ciba company in Zurich, announcing a patent on the method of production of testosterone from cholesterol.
It’s chemical crutches. It’s borrowed manhood. It’s borrowed time. But, just the same, it’s what makes bulls bulls. And, who knows, maybe tomorrow, they’ll hit on a simple dietary chemical trick that will, to a degree, bring back the power of the glands that make my own natural male hormone. Meanwhile I’ll keep taking the methyl testosterone that now gives me the total vitality to go on working and waiting for such a not impossible discovery. Here’s hoping. The nearest thing to the dietary supplement of his dreams to come along during the half-century since he wrote so eloquently about the slow ‘chemical castration of men’ is dehydroepiandrosterone (DHEA).
Included in the last term were irritability, headaches and attacks of rapid heartbeat, particularly at night, which just about completes the classic picture of the andropause. Over 20 years he treated about 500 patients with very good clinical results. These he wrote up in considerable detail in five eloquent articles, and carefully documented the improvements in each symptom on his own rating scale. He also wrote a monograph describing his method of implanting testosterone pellets into the buttocks for Organon, the company who made the implants, and this is the same method used to this day and described in the chapter in this book on treatment.