By Syed Z. Ali MD, Dorothy L. Rosenthal MD, Tehmina Z. Ali MD, Jonathan I. Epstein MD
The Atlas of Urinary Cytopathology is a generously illustrated and ordinary quantity that serves as a table reference and a realistic advisor within the diagnostically tough are of urinary cytopathology. The textual content is produced from 500 high-resolution colour photographs that completely illustrate the real facets of the cytopathology of urinary tract illness. whole insurance of urinary cytopathology is supplied; as well as complete assurance of non-neoplastic lesions, benign and borderline neoplasms and urothelial carcinoma, chapters comprise common cytology, unusual fundamental neoplasms, top urinary tract lesions, and metastatic and secondary cancers. chosen photos of the histopathologic features of the lesions also are integrated for morphologic correlation, making this article appealing to either cytopathologists and surgical pathologists. Nationally well-known specialists in urinary cytopathology and histopathology supply authoritative research of each element of urinary cytopathologic research
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Extra resources for Atlas of Urinary Cytopathology With Histopathologic Correlations
33 — Chronic cystitis with friable urothelium and bleeding. 34 — Four panels from the same bladder. Arrows depict areas of focal inﬂammatory changes with hyperemia. 35 — Two panels from the same bladder. Left panel shows focal area of inﬂammation and hyperemia, right panel shows same area after YAGlaser fulguration. These lesions typically cause bladder pain and increased voiding frequency. 36a — Colovesical ﬁstula seen cystoscopically with surrounding inﬂammation. 36b — Same colovesical ﬁstula seen grossly after open excision.
The most brilliantly colored are from uric acid, whereas the rhomboid shaped crystals are triple phosphate. The larger, pale-yellow crystals are also of urate type (Papanicolaou stain, polarized microscopy, low power). 41 — Crystalluria, voided urine. Triple phosphate (ammonium magnesium phosphate) crystals, also called “struvite,” have the characteristic rectangular, rhomboid, or the so-called “coﬃn lid” appearance. These crystals form in neutral or alkaline urine and display three to six sides and oblique ends (Papanicolaou stain, low power).
The patients suﬀer from frequency, dysuria, and suprapubic pain on ﬁlling of the bladder. Multiple urine cultures are typically negative. Submucosal hemorrhages are evident. The urothelium is benign. Eventually the bladder becomes contracted with ﬁbrosis of the muscle layer. Due to the severity and relentless nature of the symptoms for some patients, cystectomy may be undertaken. 8 — Von Brunn’s nests, histologic section. Invagination of the benign urothelium into the lamina propria can give rise to nests of urothelium within the lamina propria, which sometimes lose their connection to the surface urothelium.