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By Jeanette Wyneken, Matthew H. Godfrey

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2 Proximal humerus, adult Chelonia Starting out as tiny hatchlings weighing mydas, dry bone preparation, showing smooth articonly 30 g and measuring 6 cm in carapace length ular subchondral surface at the arrow. (CL) (Van Buskirk & Crowder, 1994), leatherbacks grow into the world’s largest turtles, with some enormous animals having been recorded at more than 900 kg in weight (Eckert & Luginbuhl, 1988). Leatherbacks reach sexual maturity at about 250 kg with a minimum CL of 120 to 140 cm, about an 8000-fold increase in mass to reach maturity (Márquez, 1990; Van Buskirk & Crowder, 1994).

Several chondrocytes in the surrounding matrix (marked with dots) demonstrate pyknotic nuclei and signs of cell death. 20) shows a fibroblastic cell within the canal at the very edge of the cartilage, showing a large bulbous cytoplasmic process (at the arrow) penetrating the cartilage matrix. , 1996). The cell next to it is a macrophage with phagolysosomes, active in the removal of cartilage matrix. 21), where the cell is in such intimate contact with the cartilage matrix that no cell membrane can be discerned at the contact zone marked by red arrows.

1996). 17). Below the growth cone tip, the canal is less specialized, filled with vascular channels and hematopoietic cells. 18). 0 cm, H & E stain), showing (1) epiphyseal cartilage that is still avascular, (2) proliferation of vascular canals penetrating the cartilaginous metaphysis, and (3) advancing ring of periosteal bone. 5 cm, H & E stain), showing (1) epiphyseal joint cartilage, (2) vascular canals penetrating through the (3) subphyseal bone plate into the epipyseal cartilage from the (4) underlying metaphyseal primary ossification center.

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